Side Effects Of Cholesterol Lowering Drugs
Statins Side Effects
Certain cholesterol lowering drugs have side effects that
include raising your risk of liver damage and kidney problems, according to a recent study done at the
University of Nottingham in the United Kingdom.
Many medications designed to reduce cholesterol in your body come from a group known as statins.
Doctors prescribe them for patients with hypercholesterolemia, or high cholesterol levels. While the body
produced cholesterol naturally, unhealthy levels are usually due to eating rich foods that contain a lot of
fat.
There are several kinds of cholesterol. One type, known as LDL or low density lipoproteins, tends to stick to
artery walls. This results in a condition called artherosclerosis, or narrowing of the arteries. Atherosclerosis is
one of the major causes of heart attacks and strokes.
High cholesterol also contributes to high blood pressure because your heart has to work harder to pump blood
through your constricted blood vessels.
Statins inhibit an enzyme in your liver that helps produce cholesterol. But there's a downside according to
Nottingham study. Long term statin use use can eventually have a negative effect, and even, in some cases, result
in liver failure.
The Nottingham research also found that statins can contribute to a condition called myositis, or inflammation
of the muscles. In addition to causing musclar pain, myositis also makes muscles weaker. As myositis progresses, it
can eventually lead to a more serious condition known as rhabdomyolysis. When you have rhabdomyolysis, your muscle
begins to muscle degrade, which produces a byproduct called myoglobin. Myoglobin passes through the kidneys and can
trigger kidney problems.
According to the Nottingham study, statins side effects can also endanger eye health, causing
cataractst to develop.
The research emphasized the importance of having regular liver function tests done if you're taking statins to
reduce LDL cholesterol. Your blood should also be tested for ?any possibility of future kidney failure.
But there's also good news from the study. While it found that side effects can occur, it also determined that
the overall risk was slight. When the possible sde effects of statins are compared to the risk of heart disease
from high cholesterol and high blood pressure, taking statins makes sense when prescribed by your doctor.
In recent years, doctors have been prescribing statins more and more often because the number of patients with
obesity, which is a major risk factor for high cholesterol and heart disease, has been growing at alarming
rates.
Recently, computer programs have been developed to help doctors identify patients with the highest probability
of experiencing stains side effects. Patients should be monitored closely if it's apprent that they need
cholesterol lowering medications, but are also more likely to be affected by side effects.
Also see a list of cholesterol medications and niacin cholesterol reduction.
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